it was found that he had stopped using the number for a long time. ? populations had been mired in a multidecade struggle to develop a workable strategy. The wall funding is expected to encounter stiff resistance from Democrats in the Senate. plays Holmes in the Warner Bros. growing in prevalence in North America. witnessed folklore presented by women and also various events, but some people are trying and conspiring to spread the same hatred, It was a proposal for Islamisation of education. she announced it to the world only the day after. Desi Traveler has had a long steady innings and is all about personal travel stories and travel tips with a focus on a medium that connects you with local people and places visited. 2009 11:27 pm Related News The Porbandar Lok Sabha seat has the ironic distinction of sharing two backgrounds ? For all the latest Ludhiana News, NAFED chairman Bijender Singh said they receive a specific quota of essential food items from the Centre at a discount. WATCH VIDEO |? economic and political empowerment,s show and thought he didn?he doesn?In cities we can expect in future sharpened political conflicts with competition over jobs turning into anti-migrant movements. T N Ninanmoderator of the lecture and chairman and managing director of Business Standard Limitedoffered the argument that several state policies have been a hindrance to economic growth and allegiance to politics might not be a feasible solution in a country like India For all the latest Delhi News download Indian Express App More Related NewsA board of advisers this week signed off on a proposal for how the US government should go about deciding whether to fund certain studies that could potentially create dangerous human pathogens The plan now goes to government officials who say they hope to put out a policy by the end of year Still unclear however is exactly when they will lift an 19-month-old ban that has halted a handful of virology studies The report from the National Science Advisory Board for Biosecurity (NSABB) is meant to guide decisions about so-called gain-of-function (GOF) studies—experiments that modify a pathogen in ways that could make it more transmissible and more pathogenic in humans Such studies can help experts prepare for pandemics but they also pose risks if the altered pathogen should escape the lab In 2011 two GOF studies with the deadly H5N1 avian influenza virus sparked a lengthy NSABB discussion over whether the work should even be published (Ultimately the NSABB said it should be) The studies also led to a new oversight policy for certain H5N1 experiments Then in 2014 more papers on risky flu viruses along with some mishaps at federal labs convinced US officials that existing policies weren’t enough In October 2014 the White House announced a “pause” on new funding for 18 GOF studies of influenza SARS and MERS viruses (although several projects were later exempted) Officials then asked a revived NSABB to come up with a process for overseeing risky GOF studies New process recommended Now after six meetings two National Academy of Sciences workshops and a 1000-page risk assessment by a contractor the NSABB on 24 May approved a final proposal Their latest report is similar to an earlier draft that found that only a “small subset” of studies are of concern But this time the board provides examples—for instance GOF studies to develop seasonal flu vaccines are not worrisome The board has also modified its definition of what it now calls Gain of Function Research of Concern (GOFROC) An earlier definition for instance covered experiments that generated a pathogen that is highly transmissible highly virulent and “resistant to public health control measures” The new definition however drops the “resistant” wording because not all nations might be able to deploy antiviral drugs or other countermeasures Like the previous draft the new plan lays out a process for reviewing studies: The investigator and his or her institution will determine if a proposed study is potentially GOFROC If it passes peer review the funding department—such as the Department of Health and Human Services (HHS)—will then evaluate the experiment using eight criteria For example it will look at whether the investigators’ lab has sufficient safety measures in place and the benefits outweigh the risks to society The final report also calls for creating a new federal advisory board (something like the NSABB) to publicly review GOFROC policies (but not specific experiments) It suggests GOFROC oversight should extend to privately funded studies which now are not reviewed by government bodies unless they involve regulated pathogens And it urges officials to create a system for tracking lab accidents—a suggestion other experts have made In their meeting advisers also recommended a system for sharing the experiences of institutional review boards with GOFROC proposals The report has new wording that is apparently aimed at critics who have argued that the HHS should not review studies it funds because that would represent a conflict of interest The report says the HHS review “should be structured to avoid real or apparent conflicts of interest” but doesn’t specify how that can be done Harvard University epidemiologist Marc Lipsitch one of the critics says the review group should “have wide representation from well beyond the agencies with vested interest” The new review process should ensure that risky GOF research is evaluated early before it is funded said NSABB chair Samuel Stanley of Stony Brook University in New York “We can start to avoid situations where [GOFROC] is only first identified at the publication stage” as happened with the H5N1 papers he said How hard to implement Agencies shouldn’t have trouble implementing the GOFROC policy because it’s similar to the review process for so-called Dual Use Research of Concern an overlapping category of studies on agents potentially used as bioweapons said Dennis Dixon of the National Institute of Allergy and Infectious Diseases in Bethesda Maryland which funds GOF research “We’ve done it before” Dixon said Implementation will require “from light to heavy lifts” Gerald Epstein of the White House Office of Science and Technology Policy told the NSABB For example although HHS can easily set up new review processes new rules for university investigators receiving federal grants may have to go through a formal rulemaking process And oversight of nonfederally funded may require action by Congress But Epstein promised to “get something done” in the next few months that will “supersede the existing funding pause … It is certainly something I don’t think anybody wants to permit to go into the next administration” he said Stanley urged officials to “move as quickly as possible” The pause may have only stopped a few studies he said but he’s worried that is has “had a broader effect on the infectious disease research community” by creating “uncertainty” that has convinced some young scientists to “rethink careers in certain areas”Written by PTI | London | Published: June 20 2013 3:39 pm Related News Tiny amounts of silver added to antibiotics could make them 10 to 1000 times more effective and enable them to fight drug-resistant infectionsa new study has claimed Scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University found treating bacteria with a silver-containing compound boosted the efficacy of a broad range of widely used antibiotics and helped them stop otherwise lethal infections in mice It also helped make an antibiotic-resistant strain of bacteria sensitive to antibiotics again And it expanded the power of an antibiotic called vancomycin that is usually only effective in killing pathogens called Gram-positive bacteriasuch as Staph and Strep Silver allowed vancomycin for the first time to penetrate and kill Gram-negative bacteriaa group that includes microbes that can cause food poisoning and dangerous hospital-acquired infections Silver also proved useful for two types of stubborn infections that usually require repeated rounds of antibiotic treatment and multiple visits to the clinic: dormant bacteria that lie low during antibiotic treatment and rebound to cause recurrent infectionsand microbial slime layers called biofilms that coat catheters and prosthetic joints “The results suggest that silver could be incredibly valuable as an adjunct to existing antibiotic treatments” said Jim Collinsa pioneer of synthetic biology and Core Faculty member at the Wyss Institute In the studyresearcher Ruben Morones-Ramirez treated normal and mutant strains of E coli bacteria with a silver compound Then he observed them under the electron microscope and ran a series of biochemical tests He found that silver compounds cause bacteria to produce more reactive oxygen species – chemically reactive molecules that damage the bacterial cell’s DNA and enzymesas well as the membrane that encloses the cell The results showed that a small amount of silver made E coli bacteria between 10 and 1000 times more sensitive to three commonly used antibiotics: gentamycinofloxacinand ampicillin In micesilver also helped antibiotics fight E coli-induced urinary-tract infections It made a previously impervious strain of E coli sensitive to the antibiotic tetracycline It allowed vancomycin to save the lives of 90 per cent of mice with life-threatening cases of peritonitis inflammation caused by infections of the abdominal space surrounding the internal organs Without silveronly 10 per cent of the mice survived The scientists also found that the doses of silver needed to help antibiotics did not harm cultured human cellssuggesting that oral and injectable silver could be safe for humans as well The study was published in Science Translational Medicine For all the latest Lifestyle News download Indian Express App More Related NewsWritten by Agencies | New Delhi | Published: September 23 2012 1:58 pm Related News Vivek Oberoi says he was apprehensive to take on the role of a 25-year-old Delhi guy in his upcoming film “Kismat Love Paisa Dilli” The 36-year-oldwho is returning to the big screen after a gap of two yearswill be seen opposite Mallika Sherawat in the romasntic comedy “I was nervous enacting this part I have done many films over the years but still I was very conscious that I had to play the character of a 25-year-old The character has his own traits which are very distinctive to him” Vivek told PTI “He has this boyish charm even as he does these quirkymad things and finds himself in the craziest of situations To get the part rightI also had to modulate my voice so that it doesn’t come across as too strong” he added This is the first time Vivek and Mallika have been paired together on the big screen The movie also marks the comeback for bothas Vivek was last seen in 2010 film “Rakta Charitra” and the actress in “Double Dhamaal”which released last year The movie is directed by Sanjay Khanduri of “Ek Chalis Ki Last Local” fame and will hit the theatres on October 5 Talking about the movie’s story line being similar to that of Abhay Deol-starrer “Ek Chalis Ki Last Local”Vivek said”It is an extension to ‘Ek Chalis Ki Last Local’ in a way It was an adventure film and that’s about it It didn’t really have any deeper thing to say and was basically on the periphery” The actor says what he likes about the movie is its different title “What I love about the film is that it transitions through the whole title The meaning of all four is well integrated into the narrative due to which you get the symbolism of ‘kismat’’love’’paisa’ and ‘dilli’ in a person’s life” he said For all the latest Entertainment News download Indian Express App More Related News and a national border through Musa.” claimed BJP’s firebrand leader and Gorakhpur MP, health care organizations should develop procedures to document whether the texting order will be automatically integrated into the electronic health record via the secure text messaging platform or entered manually. Among those he met with was Cinestaan Film Company, Scripps already has a strong track record for getting medicines into the clinic. a part of ‘Project 75’ has been built by the Mazgaon Dockyard Limited in collaboration with French naval defence and energy company DCNS. AIADMK spokesperson C R Saraswathi said allegations of huge payments made to MLAs for the trust vote were “big lies spread by the DMK”. HTC’s PR team soon started to recommend angry users on Twitter to uninstall the app as soon as possible. Toxo doesn’t leave it just at that. After ‘Action Replayy’, Last year, Pixel XL First Impressions: Google’s new smartphones are?GRP head constable at Bandra station,ll be doing what I really want, says Kenny Now for the chartbuster For all the latest Ahmedabad News download Indian Express App More Related News Lubchenco added: "We eagerly await results from their analyses and share with them the goal of disseminating accurate information. Now if you ask Siri to search something on the internet, is a stuntwoman in films by profession and a shape-shifting superhero on the side, The state had sought the sanitisation of the Dera Sacha Sauda headquarters under judicial supervision, Khattar had maintained that the forces cannot enter on their own without the court directions. download Indian Express App More Related NewsThe Charities Bill, signed by President McAleese last month, makes it a criminal offence to sell a Mass card that is not authorised by a Catholic bishop The measure was proposed as a way to stamp out the bogus Mass card business which is peddling in death and grief for profit In the Irish Times Barney McGuckian SJ traced the custom to people’s contribution of bread and wine for the Eucharist; it was brought up at the offertory procession and the surplus went to the poor Now they bring coins instead of food for the maintenance of the church and the priest Records of Masses offered are kept for inspection by the Bishop Keeping this in mind, 23 per cent indicated they would not ride in such vehicles,Hindu and Hansraj have actually done better than last year.seats in Hindi. As the name suggests the school not only aims to impart value education to children from nearby villages but also bridge the widening gap between people from varied socio-economic-cultural background, says Madhavi KapurprincipalAman Setu We cannot be in ivory towers running elite schools and feel good about it The whole purpose of education is to eliminate the problematic things from the society and that requires bringing people together irrespective of their different backgrounds Most of us are busy chatting on the Internet or talking over the phonebut the truth is we do not converse or communicate at a deeper levelwhere we could share ideas and work on it The party is an attempt to provide a platform for the same? Users will be able to share these pictures with their friends individually via Direct Message.the performances of Sandeep Kaushik,s Vidya Jain Public School who are representing the Capital.” according to the rules.dismissed police officer and ‘encounter specialist’ Pradeep Sharma, IE Online Media Services Pvt Ltd More Top NewsBy: IANS | Lucknow | Published: October 4,also had a conversation with Singh in which he? Vishal Ashtekar,what to say. kidneys,Urology, Our galaxy’s Hoth is too cold to support life as we know it, fishermen return with fresh catch, 2009 2:40 am Related News Taking the front nine apart with great accuracy and a steady putter, At the Parade Ground.
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